Detailed gene information

Genes [306]

DCL1LHYGA2ox6MRG2CRY2ATPRMT10ATX2STOESD7, TIL1, ABO4NF-YC9, HAP5CPHYACIB4OTS2LWD1, ATAN11UBC1GAI, RGA2GA3OX1TPLCSTF77ARP4AFR2GIPFT1, MED25TEM1, EDF1CIB5CUL3AVOZ1GA2ox2SUF4FRL2RCD1FBH1GA2ox4CPK33GA2ox7FBH3, AKS1, BHLH122ASH2R, TROHTA9SPA4SPL4RRP6L1NF-YC3HUB2MED13, GCT, MAB2VIM1, ORTH2OTS1, ULP1DVIP5LDL1FTVIM2RGL1AT-STUbl4FKF1, ADO3TEM2, RAV2AP1CDF5CSTF64PHLAFR1SDG26, ASHH1FLM, MAF1, AGL27EFS, SDG8GA2ox1TPS1APL, WDY, FEGA2, ATKS1ELF7PRP8, SUS2, EMB33GA3OX2RGA1UBC2EFMELF8, VIP6ABH1, CBP80CPK6FDP, BZIP27PHYBVIL3, VEL2LKP2MIR156GFVE, MSI4GLK1, GPRI1FIO1GRP7, CCR2MED18SVPAGL17CLF, SDG1SUVR5MIR156AELF3ATCMIR172ATOE1, RAP2.7PUB12FLXUGT87A2ATX1, SDG27COP1SPL3FES1CDF4GA2ox3NF-YA4JMJ15, MEE27SRO1AS1HTA8NF-YB1, HAP3ASNZESD6, HOS1ELF4SPL9FBH4, AKS3VOZ2PIF4FPASDG7, ASSH3CKB4HUB1AHL22AGL6SOC1, AGL20BRM, CHR2LRB1SPA1PRR9CCA1RFI2HULK2AKIN10, SNRK1.1MBD9GASA5RGL2MYR2FLKGID1ACOL9FLD, RSI1MIR172CUBP13PIE1LDL2SPL5SPA3BRC1, TCP18VRN1DNFFIE1, FIS3JMJ30TICPHP, CDC73AtBMI1CVIL1, VRN5LWD2ICE1, SCRMSSRP1, HMG, NFDMYB30ARP6, SUF3, ESD1SUS4DCL3ATJ3HDA9JMJ32, JMJD5PUB13LUX, PCL1CDF3REF6, JMJ12UBP26WDR5ALNK2HTA11SMZAGL16INO80AGL18SPL15PIF5, PIL6CKB3LRB2, POB1GID1BHULK3MED12, CCT, CRPFRILIF2LDGA1AtNDXMED16, SFR6CRY1FBH2DET1, FUS2SPT16XAL2, AGL14NF-YB3, HAP3CESD4PHYDFCAVRN2PHYETSFJMJ14, PKDM7B, JMJ4GA2ox8EBSAGL19CAD2, RML1, GSH1AGL24PGI1MOS1GA20ox1FWA, HDG6WRKY34, MSP3ULT1HXK1, GIN2VIP3, SKI8VIL2, VEL1MIR156BSKB1, PRMT5MIR156CATH1CIB1FDAP2MRG1CSP2, GRP2BBX19SHL1, SHLHB16, ATHB16PRR7TFL1ELF6MIR172BSUC9UBP12FTIP1GA20OX3HAM2, HAG5, HAC11FLC, AGL25, FLFMIR156DEMF1MIR156ENF-YA1, HAP2BFYAGL15BAF60, CHC1COFRL1, SUF8RGL3TFL2, LHP1MYR1DCL4HUA2RUP2, EFO2PRR5FPF1MIR156FGID1CPHYCRRP6L2SEF, SWC6RVE2, CIR1VIM3, ORTH1CDF2HLP1ATXR7, SDG25IDD8, NUCGLK2CBP20YAF9A, TAF14B, GAS41CUL4NF-YB2, HAP3BADG1, APS1CIB2LATEPRMT4AEMF2, CYR1GA20ox2PGM1MIR156HZTLVIN3COL5MSI1SRR1PRR3TOE2SIZ1FUL, AGL8HDA5VIP4TOC1LFYFLX4, FLL4BFTCDF1HDA6, RTS1NF-YC4GIS5, EMB2780LNK1HAM1CDKC;2MAF2, AGL31MAF3, AGL70MAF4, AGL69MAF5, AGL68TOE3

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Publications

Somers D E et al., 1998, Development
Strayer C et al., 2000, Science
Alabadí D et al., 2001, Science
Makino S et al., 2002, Plant Cell Physiol.
Más P et al., 2003, Nature
Más P et al., 2003, Plant Cell
Legnaioli T et al., 2009, EMBO J.
Gendron J M et al., 2012, Proc. Natl. Acad. Sci. U.S.A.

Appears in the following schemes

Circadian clock overview

Protein function

Encodes a component of the circadian clock that belongs to the PSEUDO-RESPONSE REGULATOR (PRR) family.

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Phenotype

Single mutant:
toc1 single mutant is early flowering under SD conditions only. (Conflicting results under LD conditions.) [Somers et al., 1998][Strayer et al., 2000]

Function:
Controls photoperiodic flowering response. Component of the circadian clock. Expression of several members of the ARR-like family is controlled by circadian rhythm. The particular coordinated sequential expression of APRR9, APRR7, APRR5, APRR3 and APPR1 result to circadian waves that may be at the basis of the endogenous circadian clock. Positive regulator of CCA1 and LHY expression. [Data from UniProt]

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Regulators, targets and interactors

Downstream actors

causality
RVE8 -- [Rugnone et al., 2013][Rawat et al., 2011] -- [View TAIR record]

LHY -- [Pokhilko et al., 2012][Gendron et al., 2012][Huang et al., 2012] -- [View TAIR record]

LUX, PCL1 -- [Huang et al., 2012] -- [View TAIR record]

LNK2 -- [Rugnone et al., 2013][Rawat et al., 2011] -- [View TAIR record]

PRR9 -- [Huang et al., 2012] -- [View TAIR record]

LNK1 -- [Rugnone et al., 2013][Rawat et al., 2011] -- [View TAIR record]

PRR7 -- [Huang et al., 2012] -- [View TAIR record]

GI -- [Huang et al., 2012] -- [View TAIR record]

Upstream actors

causality
PRR7 -- [Wang et al., 2010] -- [View TAIR record]

RVE8 -- [Xie et al., 2014][Hsu et al., 2013] -- [View TAIR record]

ZTL -- [Más et al., 2003][Baudry et al., 2010] -- [View TAIR record]

CCA1 -- [Wang et al., 1997] -- [View TAIR record]

LNK2 -- [Xie et al., 2014][Hsu et al., 2013] -- [View TAIR record]

FKF1, ADO3 -- [Más et al., 2003][Baudry et al., 2010] -- [View TAIR record]

PRR9 -- [Wang et al., 2010] -- [View TAIR record]

LNK1 -- [Xie et al., 2014][Hsu et al., 2013] -- [View TAIR record]

LKP2 -- [Más et al., 2003][Baudry et al., 2010] -- [View TAIR record]

Protein-protein interactions

CHE, TCP21 -- [Pruneda-Paz et al., 2009] -- [View TAIR record]

TOC1 interaction network

Downstream and upstream flowering-related genes

Physical interactions with other flowering-related proteins