Protein function
Encodes a putative exoribonuclease H.
Phenotype
Single mutant: rrp6l1 single mutant is very slightly late flowering under LD conditions. ( No data under SD conditions.).
[Shin et al., 2014] Multiple mutant: rrp6l1;
rrp6l2 multiple mutant is late flowering under both SD and LD conditions.
[Shin et al., 2014] Remarks: rrp6l1;
rrp6l2 multiple mutant has increased
FLC expression levels.
[Shin et al., 2014] Function:Acts as an important epigenetic regulator through multiple silencing mechanisms (PubMed:23555312, PubMed:25211139). Involved in association with RRP6L1 in the silencing of the solo LTR locus. Controls levels of non-coding RNAs (ncRNAs) from the solo LTR locus. Seems to function independently of the RNA-mediated gene silencing (RdDM) pathway (PubMed:23555312). Functions redundantly with RRP6L1 in the regulation of FLC locus. Participates in the maintenance of trimethylated Lys-27 (H3K27me3) at FLC locus via the regulation of antisense long non-coding RNAs (lncRNAs) and the regulation of diverse antisense RNAs derived from the FLC locus. Seems not involved in the exosomal RNA degradation (PubMed:25211139). May be involved in poly(A)-mediated RNA degradation (PubMed:18285452).
[Data from UniProt]
Regulators, targets and interactors
Downstream actors
Upstream actors
Protein-protein interactions